The date palm fruit (Phoenix dactylifera L. Arecaceae) is used in most of the countries of the world and is an essential part of the diet, especially in many Arabian countries. Phoenix dactylifera L. fruits are a rich source of sugars (glucose and fructose), vitamins (A, C, and B complex), fibers, minerals, and phenolic compounds having antioxidant and anti-inflammatory properties. This study is designed to explore the Phoenix dactylifera L. fruit for skin care. A single-blinded, placebo control trial was conducted, including 11 healthy female volunteers after their informed consent. The efficacy of the Phoenix dactylifera L. extract (4%) was evaluated in cream form after one, two, three, four, six, and eight weeks of treatment compared with the baseline. Prior to the study, the composition of the extract was analyzed to understand the underlying mechanisms by which the extract affects skin. Treating facial skin with the Phoenix dactylifera L. extract significantly improved all parameters investigated, such as skin elasticity, pigmentation, redness, brightness, and hydration and led to the improvement of the facial skin. There were no adverse reactions noted during the course of the patch test, demonstrating that the extract could be safe to apply on the skin. The Phoenix dactylifera L. fruit extract serves as a skin care ingredient that significantly improves characteristics important for perception of skin ageing and health. The efficacy of the treatment is possibly due to a combination of numerous active substances found in the Phoenix dactylifera L. extract.
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