Objective. To determine the significance of high serum ferritin observed in Indigenous Australian patients on maintenance haemodialysis in the Northern Territory, we assessed the relationship between ferritin and transferrin saturation (TSAT) as measures of iron status and ferritin and C-reactive protein (CRP) as markers of inflammation. Methods. We performed a retrospective cohort analysis of data from adult patients (≥18 years) on maintenance haemodialysis (>3 months) from 2004 to 2011. Results. There were 1568 patients. The mean age was 53.9 (11.9) years. 1244 (79.3%) were Indigenous. 44.2% () were male. Indigenous patients were younger (mean age [52.3 (11.1) versus 57.4 (15.2), ]) and had higher CRP [14.7 mg/l (7–35) versus 5.9 mg/l (1.9–17.5), ], higher median serum ferritin [1069 µg/l (668–1522) versus 794.9 µg/l (558.5–1252.0), ], but similar transferrin saturation [26% (19–37) versus 28% (20–38), ]. We observed a small positive correlation between ferritin and TSAT (, ), no correlation between ferritin and CRP ( = 0.001, ), and positive association between high serum ferritin and TSAT (), Indigenous ethnicity (), urea reduction ratio (), and gender () after adjustment in mixed regression analysis. Conclusion. Serum ferritin and TSAT may inadequately reflect iron status in this population. The high ferritin was poorly explained by inflammation.
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2klDeoP
via IFTTT
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δημοφιλείς αναρτήσεις
-
Treatment effectiveness holds considerable importance in the association between service quality and satisfaction in medical service studies...
-
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2p08wUI via IFTTT
-
Background. Transseptal puncture (TSP) can be challenging. We compared safety and efficacy of a modified TSP technique (“mosquito” technique...
-
FS Teni, AS Surur, A Hailemariam, A Aye, G Mitiku, AE Gurmu, B Tessema Annals of Medical and Health Sciences Research 2015 5(6):454-460 ...
-
Abstract Purpose Gastric cancer (GC) is one of the fatal malignancies worldwide with high occurrences but poor outcomes. bFGF has been s...
-
We provide excellent essay writing service 24/7. Enjoy proficient essay writing and custom writing services provided by professional academi...
-
Daily Mail Sarah was diagnosed with the cancer that killed Steve Jobs Daily Mail The symptoms Sarah Smith experienced on and off for...
-
Keratoconus (KC) is a corneal thinning disorder that leads to loss of visual acuity through ectasia, opacity, and irregular astigmatism. It ...
-
The Role of the Mammalian Prion Protein in the Control of Sleep. Pathogens. 2017 Nov 17;6(4): Authors: Roguski A, Gill AC Abstract ...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου