Primary leiomyosarcoma of frontoethmoidal sinus

Karuna Jha, Ishita Pant, Rima Kumari, Gurbachan Singh, Sujata Chaturvedi

Astrocyte 2016 3(2):100-103

Leiomyosarcoma is rarely encountered in the sinus and skull base. The common location of this tumor is the female genital tract and the limbs because of the preponderance of smooth muscle at these sites. Clinically, these tumors are very aggressive, and the prognosis is poor. Here, a report of a bilateral frontoethmoidal leiomyosarcoma with review of literature is presented. A 28 year-old male presented with a gradually progressive painful frontal swelling with episodes of headache. The patient underwent a frontal craniotomy and the tissue was sent for histopathological examination. Histopathological diagnosis of leiomyosarcoma was made with the routine hematoxylin and eosin stain and immunohistochemical markers. Although there have been case reports in the literature describing the primary intracranial leiomyosarcoma involving the frontal and ethmoidal sinuses, this lesion continues to cause difficulty in preoperative diagnosis. The case is reported for the rarity of its location and the diagnostic challenge it poses.

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