There is an urgent need for evidence-based internationally agreed guidelines for the assessment of neonates at risk of developing early-onset sepsis

Commentary on: Mukhopadhyay S, Taylor JA, Von Kohorn I, et al. Variation in sepsis evaluation across a national network of nurseries. Pediatr 2017;139:e20162845.

Implications for practice and research

An optimal approach for early-onset sepsis (EOS) risk assessment in neonates would allow for standardised quality of care and would minimise disparities in management.

There is a need for the evaluation of current practices and outcomes in managing neonates at risk for EOS, as well as the development of internationally agreed evidence-based guidelines.

Context

Neonatal sepsis is a leading cause of morbidity and mortality. However, there are substantial differences in the practice of risk assessment of neonates with suspected EOS. Attempts have been made to streamline the management pathways in the USA, UK and elsewhere through publication of the national guidelines.1 2 A rational approach is needed to prioritise the treatment of sick babies, while streamlining the management pathways for well...

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