Παρασκευή 23 Φεβρουαρίου 2018

Immunohistochemical Detection of p16 in Clinical Samples.

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Immunohistochemical Detection of p16 in Clinical Samples.

Methods Mol Biol. 2018;1726:123-142

Authors: Karpathiou G, Peoc'h M

Abstract
P16 immunohistochemical expression, a surrogate marker of the retinoblastoma pathway, has become a major adjunct in the routine practice mostly of cervical and head/neck pathology, but with other indications too. In this chapter, a detailed immunohistochemical technique for the detection of p16 is described, followed by indications and interpretation of its expression in uterine, ovarian, vulvar, penile, head-and-neck, melanocytic, and other pathologies.

PMID: 29468549 [PubMed - in process]



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