Deciphering the roles of FOXO1 in human neoplasms

Abstract

Neoplasms constitute an enormous burden and contributed to an estimated 8.2 million deaths in 2012 worldwide. FOXO1 (forkhead box O1), a member of the forkhead box (FOX) family, is a transcriptional factor involved in diverse cellular functions. Herein, we concentrate on recent studies of the antineoplastic roles of FOXO1 in neoplasms. This review may serve as a guide for future research and identify FOXO1 as a potent therapeutic target in neoplasms. This article is protected by copyright. All rights reserved.

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