Needle use and dosimetric evaluation in cervical cancer brachytherapy using the Utrecht applicator

Publication date: Available online 29 November 2017
Source:Radiotherapy and Oncology
Author(s): Milena Smolic, Chèrita Sombroek, Monique C.W.M. Bloemers, Baukelien van Triest, Marlies E. Nowee, Anton Mans
Background and purposeTo analyse the clinical use of needles and examine the feasibility to meet the planning criteria in three fractions of cervical cancer brachytherapy. Furthermore, to investigate whether the needles with the largest discrepancy between application and loading are essential to treatment planning.Materials and methodsFor 22 patients we analysed the applied and loaded needle patterns, and examined the dosimetric results for small (<30 cm³) and large (≥30 cm³) CTVHR. We removed from the clinical plans (CP) the needles applied most, but with the lowest loading frequency and intensity and re-optimized these plans (RP).ResultsOn average 5.8 needles were applied and 4.8 loaded per fraction, with average intensity 22% (17% for small, 29% for large CTVHR). Mid-lateral needles were applied and loaded most frequently and intensely. The average CTVHR D90% prescribed dose was 88.8 Gy (SD 4.2) EQD210, the average OAR D2cm3 limit was respected. Omitting the mid-ventral needles, minimal statistically significant differences were found in dose distributions between RP and CP.ConclusionsApplying on average 5.8 needles per fraction it was possible to meet the planning criteria for targets and OARs in three BT fractions for both small and large CTVHR. The mid-ventral needles were not essential in treatment planning, unless situated in the vicinity of the GTVres.



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