Two cases of spontaneous remission of non-parasitic chyluria

Publication date: Available online 4 May 2017
Source:Clinical Biochemistry
Author(s): Damodara Rao Mendu, Hillel Sternlicht, Lakshmi V. Ramanathan, Melissa S. Pessin, Martin Fleisher, Guido Dalbagni, Edgar A. Jaimes, Anna Kaltsas, Ilya G. Glezerman
ObjectivesChyluria is a medical condition with presence of chyle in urine. The disease is most prevalent in South East Asian countries mostly caused by parasitic (Wuchereria bancrofti) infections. Our objective was to investigate the spontaneous remission of non-parasitic chyluria.Design and methodsThe spontaneous remission of non-parasitic chyluria cases were worked out with diagnostic investigations, clinical assessment and studied with details of all aspects with evolutionary totality.ResultsWe present two patients who presented to nephrology clinic with symptoms of milky urine and painless hematuria. Midnight blood smear was negative for filarial parasites. Urine culture was without mycobacteria. Urine cytology and IgG western blot for cysticercus were negative. Imaging for a lymphatic leak by lymphoscintigraphy was unrevealing. Chyluria resolved spontaneously in both patients.ConclusionsIn our cases, radiologic visualization via lymphoscintigraphy was unrevealing. The patients were managed conservatively and fortunately underwent spontaneous remission marked by the disappearance of chyluria within several months of her initial diagnosis. In our opinion this spontaneous remission could be due to unrevealed lymphatico-renal fistula collapse or sclerosis of lymphatics caused by contrast media.



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