Rhabdomyosarcoma (RMS) is an aggressive family of soft tissue tumors that most commonly manifests in children. RMS variants express several skeletal muscle markers, suggesting myogenic stem or progenitor cell origin of RMS. In this review, the roles of both recently identified and well-established microRNAs in RMS are discussed and summarized in a succinct, tabulated format. Additionally, the subtypes of RMS are reviewed along with the involvement of basic helix-loop-helix (bHLH) proteins, Pax proteins, and microRNAs in normal and pathologic myogenesis. Finally, the current and potential future treatment options for RMS are outlined.
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2ri5snh
via IFTTT
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δημοφιλείς αναρτήσεις
-
Abstract The incidences of thyroid cancer keep rising worldwide over the past few decades. Although most thyroid cancers are indolent and ...
-
Abstract Amyloid beta peptide (Aβ), the main component of senile plaques of Alzheimer’s disease brains, is produced by sequential cleavage ...
-
ACS Nano DOI: 10.1021/acsnano.7b02426 from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2h1neaG via...
-
Coexistence of t(5;17)/NPM1-RARA and t(9;22)/BCR-ABL1 in chronic myeloid leukemia at initial diagnosis Juvenile myelomonocytic leukemia: a s...
-
We set out to estimate net survival trends for 10 common cancers in 279 cancer registry populations in 67 countries around the world, as par...
-
Abstract Background Hyponatremia is associated with the increased risk of early and late mortality in patients with cardiac disease. Thi...
-
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2B38rkA via IFTTT
-
Publication date: Available online 17 January 2018 Source: Journal of Infection and Chemotherapy Author(s): Nobuyasu Hirai, Kei Kasahara, ...
-
Background Epidemiology of Neisseria meningitidis has been changing since the introduction of universal vaccination programmes against meni...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου