Brain metastases (BRM) occur frequently in non-small cell lung cancer (NSCLC) and present a substantial unmet medical need. Prior literature on global BRM prevalence, treatment patterns, costs, and outcomes typically has described a subset of these factors. The primary objective of this systematic literature review was to summarize BRM-related epidemiology, treatment patterns, costs, and survival of patients with NSCLC in the United States, European Union, and Japan.
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