Τετάρτη 25 Ιανουαρίου 2017

Janus-kinase inhibitors display broad anti-itch properties – a possible link via the TRPV1 receptor

The antipruritic effect of JAK inhibitors is fast and sustained in dogs with atopic dermatitis and in human patients with psoriasis. The inhibitory profiles of these molecules might be more related to their direct inhibition of TRPV1 rather than that of JAKs.

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