Epicutaneous exposure to allergens through the skin is considered to be an important route of sensitization.1,2 Allergen sources, such as mites, insects, fungi, and pollen, contain proteases, which are frequently allergens themselves.3 Recent studies using murine models of sensitization via skin4 or airways5-7 revealed that the protease activity of a model protease allergen, papain, is essential to the induction of inflammation at the sensitization sites and serum IgE/IgG1 responses. However, the role of allergen protease activity in effector-phase responses against low-dose antigen encounters after epicutaneous sensitization currently remains unknown.
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2BGx0sj
via IFTTT
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δημοφιλείς αναρτήσεις
-
Objectives To optimise medical students’ early clerkship is a complex task since it is conducted in a context primarily organised to take ca...
-
Abstract Purpose Overcoming the flaws of current data management conditions in head and neck oncology could enable integrated informatio...
-
1 abqls-210rm.html Read the latest Journal of Clinical Neurophysiology - Vol. 37, No. 1, January 2020.eml 2 agx3v-nxz96.html Read the late...
-
Cone-beam CT (CBCT) is a widely used intra-operative imaging modality in image-guided radiotherapy and surgery. A short scan followed by a f...
-
by Yanwei Li, Haifeng Liu, Wei Zeng, Jing Wei An increase in the osmolarity of tears induced by excessive evaporation of the aqueous tear p...
-
http://ift.tt/2p41efZ
-
-
Abstract Bromodomain proteins function as epigenetic readers that recognize acetylated histone tails to facilitate the transcription of t...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου