Antioxidants, Vol. 7, Pages 5: Singlet Oxygen and Free Radical Reactions of Retinoids and Carotenoids—A Review

Antioxidants, Vol. 7, Pages 5: Singlet Oxygen and Free Radical Reactions of Retinoids and Carotenoids—A Review

Antioxidants doi: 10.3390/antiox7010005

Authors: Ruth Edge T. Truscott

We report on studies of reactions of singlet oxygen with carotenoids and retinoids and a range of free radical studies on carotenoids and retinoids with emphasis on recent work, dietary carotenoids and the role of oxygen in biological processes. Many previous reviews are cited and updated together with new data not previously reviewed. The review does not deal with computational studies but the emphasis is on laboratory-based results. We contrast the ease of study of both singlet oxygen and polyene radical cations compared to neutral radicals. Of particular interest is the switch from anti- to pro-oxidant behavior of a carotenoid with change of oxygen concentration: results for lycopene in a cellular model system show total protection of the human cells studied at zero oxygen concentration, but zero protection at 100% oxygen concentration.

from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2C6BEfV
via IFTTT