Key Points
- Antegrade and retrograde dissection/re-entry techniques are frequently utilized in contemporary CTO PCI, especially for complex lesions.
- One-year outcomes with modern dissection/re-entry techniques appear favorable and comparable with those achieved after intraplaque crossing, supporting their increased use.
- Randomized data on the procedural safety, efficiency, and long-term outcomes of subadventitial CTO PCI techniques are needed.
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