Gq protein-induced apoptosis is mediated by AKT kinase inhibition that leads to protein kinase C-induced c-Jun N-terminal kinase activation. [Withdrawals/Retractions]

VOLUME 286 (2011) PAGES 31022–31031This article has been withdrawn by the authors. The gJNK panel from SK-OV-3 cells was reused in the gJNK panel from OVCAR-3 cells in Fig. 1A. The tubulin panel in Fig. 2C was reused as the right g-p38α in Fig. 4B, and as the IP: gMLK3 and IB: gMLK3 panel in Fig. 6F. The left p473 AKT immunoblot and the right p308 AKT immunoblot in Fig. 4D were inappropriately manipulated. Also, the right AKT immunoblot from Fig. 4D was reused as the right AKT immunoblot in supplemental Fig. S2B. Lanes 2 and 3 of the JNK immunoblot in Fig. 6D were reused in the JNK immunoblot from Fig. 6E. The MKK4 immunoblots in Fig. 7A were duplicated. Lanes 2 and 3 and lanes 5 and 6 of the upper JNK immunoblot in Fig. 7C were reused in the lower left and right JNK immunoblots, respectively. The AKT immunoblot from SVOG-40 cells in supplemental Fig. S2A was reused in the AKT immunoblot from SVOG-40 cells in supplemental Fig. S2B. The pc-Src panel from supplemental Fig. S3A and the right AKT immunoblot from supplemental Fig. S3C were manipulated inappropriately. The authors state that these errors do not affect the results or conclusions of the work.

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