The identification and quantitation of gamma-hydroxybutyric acid (GHB) in beverages is considered challenging in forensic evidence. GHB has been implicated in many cases of suspected surreptitious administration with the purpose of increasing victim vulnerability to sexual assault. For this reason, some studies have focused on the determination of GHB in spiked alcoholic and non-alcoholic beverages [1]. However, previously the presence of endogenous (or naturally occurring) GHB in beverages has been reported in various publications [2–4].
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