Self-Reported Physical Quality of Life Before Thoracic Operations Is Associated With Long-Term Survival.

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Self-Reported Physical Quality of Life Before Thoracic Operations Is Associated With Long-Term Survival.

Ann Thorac Surg. 2017 Feb;103(2):484-490

Authors: Al-Ameri M, Bergman P, Franco-Cereceda A, Sartipy U

Abstract
BACKGROUND: The aim was to analyze the association between baseline self-reported health-related quality of life and long-term survival after thoracic operations.
METHODS: In a prospective population-based cohort study, we included patients scheduled for thoracic operations and obtained information about preoperative health-related quality of life using the validated quality-of-life instrument Short Form-36. Patients were categorized according to higher or lower physical and mental component scores, compared with an age- and sex-matched reference population. The primary outcome measure was all-cause mortality and was ascertained from Swedish national registers. We used Cox regression for estimation of hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between preoperative physical/mental quality of life and long-term survival while adjusting for differences in baseline characteristics, cancer stage, histopathologic process, and other factors.
RESULTS: We included 249 patients between 2006 and 2008. During a median follow-up time of 8.0 years, 119 patients (48%) died. Having a physical component summary score less than reference was significantly associated with mortality (multivariable adjusted HR 2.02, 95% CI: 1.34 to 3.06, p = 0.001). A mental component summary score less than reference was not associated with mortality (adjusted HR 1.32, 95% CI: 0.84 to 3.06, p = 0.233).
CONCLUSIONS: In patients who underwent thoracic operations, a self-reported physical quality of life lower than reference value was associated with significantly worse survival independent of histopathologic process, cancer stage, extent of operations, and other patient-related factors. The preoperative mental component of quality of life was not associated with long-term survival.

PMID: 27666786 [PubMed - indexed for MEDLINE]

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