Genomic analysis of type strain Paenibacillus aceti L14 T , a highly efficient producer of pyrazines

Abstract

Paenibacillus aceti L14^T (CGMCC 1.15420 = JCM 31170) is a novel species isolated from the solid-state acetic acid fermentation culture of traditional Chinese vinegar. The strain is able to biosynthesize the pyrazines, including 2,3-diisobutylpyrazine, 2-isobutyl-3-methylpyrazine and 1-(5-isobutyl-2-pyrazinyl)-1-propanone. Genome sequencing of L14 was performed to gain insights into the genetic elements involved in the biosynthesis of pyrazines. The genome of L14 contains 5,611,962 bp with a GC content of 47.92 mol%, 5147 protein coding genes, 92 tRNAs, 20 rRNAs and four sRNAs. The strain L14 also contains complete biosynthetic pathways of valine, leucine and isoleucine, and contains genes for encoding threonine dehydratase and ketol-acid reductoisomerase. This genome sequence provides a basis for elucidating the possible mechanism for the biosynthesis of pyrazines.

from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2qpARk4
via IFTTT