Breast cancer is among the most frequent tumors worldwide and over 200,000 women will develop the disease in the United States in 2016 [1]. Breast cancer is a heterogeneous disease, clinically classified based on the presence of hormonal receptors for estrogen (ER) and progesterone (PR), and the expression/amplification status of the human epidermal growth factor receptor 2 (HER2) protein/oncogene [2].
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