Τρίτη 3 Ιανουαρίου 2017

Quorum sensing controls the Pseudomonas aeruginosa CRISPR-Cas adaptive immune system [Microbiology]

CRISPR-Cas are prokaryotic adaptive immune systems that provide protection against bacteriophage (phage) and other parasites. Little is known about how CRISPR-Cas systems are regulated, preventing prediction of phage dynamics in nature and manipulation of phage resistance in clinical settings. Here, we show that the bacterium Pseudomonas aeruginosa PA14 uses the...

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