Τρίτη 31 Ιανουαρίου 2017

Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications [Immunology and Inflammation]

Macrophage activation is a critical step in host responses during bacterial infections. Ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine metabolism, has been well studied in epithelial cells and is known to have essential roles in many different cellular functions. However, its role in regulating macrophage function during bacterial infections...

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