Local extension staging of sinonasal tumors: retrospective comparison between CT/MRI assessment and pathological findings.

Local extension staging of sinonasal tumors: retrospective comparison between CT/MRI assessment and pathological findings.

Clin Otolaryngol. 2017 Jan 07;:

Authors: Mortuaire G, Camous D, Vandenhende-Szymanski C, Dubrulle F, Chevalier D

Abstract
OBJECTIVES: To assess the reliability of clinical staging with CT and MRI in sinonasal cancers.
METHODS: We conducted a retrospective review of patients who underwent surgery for a sinonasal cancer. The 7(th) edition of the TNM classification was used to establish tumor staging. Standardized preoperative CT/MRI staging was compared with the pathological staging based on specimens obtained during surgery from each subsite within and around the tumor.
RESULTS: We analyzed data from 68 patients between January 2010 and December 2014. A comparison of cT and pT stages was established for 49 naso-ethmoidal and 16 maxillary tumors. Clinical staging for naso-ethmoidal cT1 and maxillary cT2 was consistent with pathological results. Clinical staging for naso-ethmoidal cT2, cT3 and cT4b was overstated in comparison with pT findings. The positive predictive value of imaging was less than 65% for the lamina papyracea, the cribriform plate, the dura, and the frontal and sphenoid sinuses. Sensitivity was over 75% for each anatomical site except for the cribriform plate (73.3%) and the sphenoid sinus (57.2%).
CONCLUSION: Systematic pathologic analysis of the anatomical areas around the sinonasal cancer has to be applied in further studies to improve our therapeutic management. CT/MRI mapping cannot replace accurate assessment of tumor extension during surgery. This article is protected by copyright. All rights reserved.

PMID: 28063243 [PubMed - as supplied by publisher]

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