First Clinical Report of Proton Beam Therapy for Post-Operative Radiotherapy for Non-Small Cell Lung Cancer

We investigated the survival outcomes and early toxicity profile of post-operative radiation therapy (PORT) with proton beam therapy (PBT) versus intensity modulated radiation therapy (IMRT) for non-small cell lung cancer in a cohort of 61 patients with positive microscopic margins and/or positive N2 lymph nodes. We found that post-operative PBT in locally-advanced NSCLC is well-tolerated and has similar excellent short-term outcomes when compared with IMRT.

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