Epigenetics is the process of heritable changes of the chromosome without changing the DNA sequence itself [1]. Distinctive processes that drive alterations of the epigenome include DNA methylation, RNA associated silencing and histone (de)acetylation [1]. Epigenetic changes such as global hypomethylation, particularly at centrometric repeats, as well as hypermethylation, often occurring in CpG islands, are frequently present in cancer [2]. Hypomethylation has been linked to genomic instability, while CpG island hypermethylation is affecting gene expression by altering the chromatin structure [3].
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Abstract Determining the cause of unexplained death in all age groups, including infants, is a priority in forensic medicine. The triple r...
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This paper presents an adaptive multiuser transceiver scheme for DS-CDMA systems in which pilot symbols are added to users’ data to estimate...
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Abstract In this paper we present the study of a skull belonging to a young male from the Italian Bronze Age showing three perimortem inju...
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Find out more about the wide range of A Levels and full time courses available at Longley Park Sixth Form College, the only independent Sixt...
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Abstract To measure integral doses in image-guided radiation therapy, we developed an integral condenser dosimeter comprising a disposable...
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Objectives. To assess the association between short-term postoperative cognitive dysfuction (POCD) and inflammtory response in patients unde...
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