Basal cell carcinoma (BCC) is the most prevalent type of skin cancer. Numerous studies have reported on the rising incidence of BCC causing a major burden on current health care systems 1. Current management relies on the histopathological subtype of a punch biopsy and this becomes more and more relevant due to the increasing use of non-surgical treatments. However the reliability of a punch biopsy in subtyping BCC has been questioned. The aim of this systematic review was to judge the reliability of a punch biopsy in accurately subtyping primary BCC.
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