INVESTIGATION OF ANTIOXIDANT AND ANTI-INFLAMMATORY PROPERTIES OF BURDOCK THICK EXTRACTS ON THE MODEL OF BENIGN PROSTATIC HYPERPLASIA (BPHP) IN RATS

2016-09-28T01-17-06Z
Source: Journal of Molecular Pathophysiology
Shchokina Catherine, Ulanova Vera.
Introduction. Benign prostatic hyperplasia (BPHP) is one of the most common diseases in men middle-aged and elderly. In this regard, search and study of new effective and safe medicines with prostatoprotective effect is important and actual. Methods. BPHP model reproduced the intraperitoneal administration of sulpiride male rats, 40 mg / kg for 30 days. Thick Burdock extracts at a dose of 75 mg / kg and reference drug prostaplant forte, 35 mg / kg were administered intraperitoneally in a medical mode 31 to day 52 of the study. Results. The administration of thick extract of burdock roots contributed to the reliable normalization of acid phosphatase activity in serum of animals, as it is evidenced by the absence of significant differences of indicator of the treated animals from the same indicator in the groups of animals with intact control. The administration of thick extract of burdock roots contributed to a significant inhibition of LPO processes, normalization of reduced glutathione and diene conjugates in the serum levels of thiobarbituric acid active products and reduced glutathione in the homogenate of the prostate. The effect of the indicators mentioned above thick extract of burdock roots was not significantly inferior to the effect of the drug compared with Prostaplant Forte. Thick extract of burdock leaves inferior to thick extract of burdock roots and the reference drug by normalizing influence on the activity of acid phosphatase, the level of reduced glutathione and diene conjugates in blood serum of the experimental animals. Conclusions. The one of the most important components of the mechanism of the prostate protective action of burdock thick extracts in benign hyperplasia of the prostate gland are their anti-inflammatory and antioxidant action wich are not inferior to the reference drug Prostaplant Forte.


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The activities of Bangladesh water development board on the social environment of Bhadrabila union, Narail sadar upazila, Bangladesh

2016-09-28T00-29-17Z
Source: Asian Journal of Medical and Biological Research
Rimi Bhattacharjee, Molla Rahman Shaibur and Md. Amit Hasan.
The study was conducted at Bhadrabila union, Narail sadar upazila, Narail in Bangladesh. The study period was carried out during September to December, 2013. In the selected areas, the study was conducted on 375 persons. The collected information was totally interview and observation based study. In the study area the highest age distribution was 50% in 21-40 years. The second highest was 39% for 41-60 years. The third highest was 7% for the year of 1-20. The lowest age distribution was for the year of 60 and above. This study found that the highest respondents of 39% are the member of 3-4 family member range. 32% respondents are in the member of 5-6 family member range. 12% respondents are in the member of 7-8 family member range. This study represent that 18% houses were kacha, 27% houses were tin shade 29% half building and 26% house were building. Almost 3% respondents were in class 1-3, 31% were in class 4-6, 46% were in between class 7-9, 10% in S.S.C level and left 9% were in above S.S.C level. Almost 79% had sanitary latrine. . It was found that 28% peoples were and poor their monthly income was 3,000-6,000 taka, 40% peoples were middle class their monthly income was 6,000-9,000 taka, about 24% peoples were rich their monthly income was 9,000-12,000 and lest 8% peoples income were 12,000+. 90% tube wells were arsenic free and only 10% tube wells are arsenic contaminated. About 77% were related with the BWDB and rests 13% were not the beneficiary of the BWDB. About 86% respondants were benifited by the activities of the BWDB. About 100% of respondents are fully satisfied by the activities of BWDB in arsenic test. It was shown that the social life of the respondents of Bhadrabila Union Parisad was getting better. The most important thing is almost 100% of the respondents were satisfied by the activities of BWDB.


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Excavation of irrigation canal changes the cropping pattern in 2013-14: Auria Union, Narail, Bangladesh

2016-09-28T00-29-17Z
Source: Asian Journal of Medical and Biological Research
Md. Amit Hasan, Molla Rahman Shaibur, Md. Shamsur Rahman, Md. Atiqur Rahman, Shaswata Biswas, Rimi Bhattacharjee and Md. Maruf Shaikah.
The principal crop during winter is Bororice and it occupies about 70% of crops. Being a country of 140 million inhabitants, agriculture is still the major water using sector in order to feed a growing population where at least 40 million people do not have a square meal. Recently, Bangladesh Water Development Board (BWDB) launched some projects to various water user groups for maintenance and expenditure recovery. Chenchuri Irrigation Sub Project is under South-West Area Integrated Water Resources Planning and Management Project (SWAIWRPMP). The project area covers the South Western Narail District along with Auria Union at Narail Sadar Upazila. Data were collected from 150 farmers of 6 villages in Auria Union. This research investigates the overall cropping pattern in Auria Union, Narail Sadar Upazila, before the construction of canal (during 1987-88), after the construction of canal (during 2009-10)and after re-excavation of canal (2012-13). The result showed that, before the construction of canal (during 1987-88) there were 5 types of cropping pattern and after the construction of canal (during 2009-10) there were 6 types of cropping pattern. But after re-excavation of canal (2012-13), 12 types of cropping pattern were recorded. Among them, the T. Aman and Boro were the most prominent cropping pattern. In Kharif 1, Kharif 2 and Rabi seasons, various types of crops were cultivated. Such as Aus, B. Aman, T. Aman, Boro, Jute, Sesame, Summer vegetables, Chilly, Garlic, Chickpea, Lentil, Mustard, Onion, Sugarcane, Turmeric, Wheat, Winter vegetables etc. The result revealed that, the re-excavation of canal have significantly positive impact on the Boro, Wheat, Turmeric, Chilly, Chick pea, Sugarcane, Lentil production. The Boro rice cultivation increased significantly day by day and it replaced other crops gradually. Because, farmers get irrigation water easily and cheaply from canal in Rabi season (16 October 15 March). The present study showed that, the excavation of irrigation canal completely changes the cropping pattern at auriaunion in Narail, Bangladesh.


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Impact of educational intervention regarding anaemia and its preventive measures among adolescent girls of Government Commerce College of Gandhinagar city, Gujarat, India

2016-09-27T11-20-34Z
Source: International Journal of Medical Science and Public Health
P B Verma, Nilesh Thakor.
Background: Adolescent girls are at a high risk for anaemia and malnutrition. Objective: To assess knowledge of adolescent girls regarding anaemia and its preventive measures before and after educational interventional training. Material and Methods: The present study was an interventional study, undertaken in purposively selected Government Commerce College of Gandhinagar city during JulyAugust 2016 by Department of Community Medicine, GMERS Medical College, Gandhinagar. Total 100 adolescent girls between the age group of 1719 were included after written informed consent. Baseline knowledge of adolescent girls regarding anaemia and its preventive measures was assessed by pre-designed, pre-tested and semi-structured questionnaire. Single educational interventional training for 45 minutes was given to the selected adolescent girls. Postintervention knowledge of students for the same was assessed after training. Thus collected data was analyzed using SPSS 17 (trial version). Result: Baseline knowledge of the adolescent girls regarding causes, signs, and symptoms of anaemia and dietary sources of iron was 21%, 23%, and 40%, respectively which was significantly increased to 64%, 66%, and 72%, respectively after the intervention. Baseline knowledge of the adolescent girls regarding factors which inhibit and increase iron absorption was 25% and 4%, respectively which was significantly increased to 55% and 41%, respectively after the intervention. Baseline knowledge of the adolescent girls regarding treatment of anaemia was 30% which was significantly increased to 79% after the intervention. Conclusion: There was a significant improvement in the knowledge regarding anaemia and its preventive measures among adolescent girls of college after our single educational session.


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Concomitant aortic regurgitation is a predictor of outcome after surgical aortic valve replacement in patients with severe aortic stenosis

2016-09-27T11-20-34Z
Source: International Journal of Medical Science and Public Health
Prashant Mishra, Chandan Kumar Ray Mohapatra, Jayant V Khandekar, Chaitanya Raut, Harsh S Seth, Ganesh Kumar K Ammannaya, Jaskaran Singh, Vaibhav Shah.
Background: Concomitant aortic regurgitation (AR) might worsen the prognosis of severe aortic stenosis (AS). But the prognostic value of concomitant AR in patients operated for severe AS is not addressed. Objective: The aim of this study was to assess the impact and association of presence and severity of concomitant AR in patients operated for severe AS on long-term left ventricular (LV) function, functional capacity, and mortality. Materials and Methods: Study group consisted of 200 patients operated due to severe AS retrospectively. The patients were divided into AS group (100 patients with AS without AR or with mild AR) and AS+AR group (100 patients with AS and moderate, severe or very severe AR). Follow-up included a clinical examination and echocardiography 530 months after AVR. Result: Patients in AS group had improved symptoms than AS+AR group. The patients with postoperative follow-up in AS group had lower LV volume indices than patients in AS+AR which was statistically significant(AS group; LVEDVi - 67±9.1, LVESVi - 22±7.2 compare to AS+AR group; LVEDVi - 84±21.3, LVESVi - 34±11, p-value

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Knowledge, attitude and practice regarding hepatitis B among medical students

2016-09-27T07-06-45Z
Source: International Journal of Community Medicine and Public Health
Syed Faisal Hussain, Sultan Rizwan Ahmad, Osman Mohammed Muslehuddin, Husam Mohammed Muslehuddin.
Background: Hepatitis means inflammation of the liver cells. Main cause of hepatitis is viral infection by hepatitis B virus. Hepatitis B is a serious, global, public health problem that gives rise to hepatocellular carcinoma with a mortality rate of about 600000 people worldwide. Medical students are also vulnerable to acquire this infection. Methods: A cross-sectional study aimed to evaluate knowledge, attitude and practice regarding spread, risk factors, diagnosis and treatment of Hepatitis B was undertaken amongst 341 undergraduate medical students using a standardized questionnaire. In addition to this awareness regarding post exposure prophylaxis and vaccination status of hepatitis B among the students were also studied. Results: In the present study 98.8% of medical students had correct knowledge regarding vaccine for hepatitis B. Study showed good knowledge regarding spread and risk factors for hepatitis B. 98.5% of the students gave the correct answer that hepatitis B is diagnosed by hepatitis markers test. Regarding treatment, 98.2% said that vaccination is the choice for treatment of hepatitis B. With respect to post exposure prophylaxis 97.1% said that vaccination is main source of post exposure prophylaxis and 91.8% said that HBIg is used for post exposure prophylaxis. Regarding the vaccination status of students for hepatitis B, 26.7% were fully vaccinated and 36.4 % were partially vaccinated and 37% were unvaccinated. Conclusions: This study showed that knowledge and attitude of medical students are good towards hepatitis B but practice is not sufficient as 1/3rd of students are unvaccinated.


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Two stage flexor tendon reconstruction in hand: our experience

2016-09-27T06-28-20Z
Source: International Journal of Research in Medical Sciences
Tawheed Ahmad, Mir Mohsin, Mohammad Inam Zaroo, Sheikh Adil Bashir, Adil Hafeez Wani, Haroon Rashid Zargar, Altaf Rasool, Peerzada Umar Farooq Baba, Akram Hussain Bijli, Summaira Jan, Saima Rashid, Shabir Ahmad Langoo, Mushtaq Ahmed Bhat.
Background: Flexor tendon injuries in the digital flexor sheath area (zone II) are the most difficult to treat and remain a focus of both clinical attention and basic investigations. This prospective study was designed to evaluate the results of staged zone II flexor tendon repair. Methods: Seventy digits in thirty five patients were treated by Two Stage flexor tendon reconstruction and followed for an average of one and a half year. The procedure included placing a silicone catheter (cut to desire size) as an active implant and reconstruction of A2, A4 or both pulleys if damaged in first stage. During the second stage (performed three to eight months later), tendon graft replaced the silicone catheter in the pseudo sheath formed around the catheter. The proximal end of the transplanted tendon was fixed with flexor digitorum profundus tendon of respective finger using the Pulvertaft method, and the distal end of the graft was fixedwith the distal stump of respective flexor digitorum profundus tendon. Early controlled motion protocol was instituted in all cases. Results: As per Buck Gramcko scale total active motion obtained was Excellent in 70%, Good in 20%, Fair in 7.1%, and Poor in 2.9% of patients. Conclusions: Flexor tendon reconstruction using two stage tendon reconstructions is an effective way to restore digital tendon function in delayed zone II flexor tendon injuries.


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