Dermatologic Surgery

Outcomes for Basal Cell Carcinoma Treated With Vismodegib Extended Alternate Day Dosing No abstract available

Commentary on Transungual Excision of Glomus Tumors No abstract available

Trends in the Incidence of Bowen Disease Based on a Single-Center Study in the Netherlands BACKGROUND Incidence trends of nonmelanoma skin cancer show an increase. Few data have been published about the incidence of Bowen disease (BD). Three previous studies, conducted more than 15 years ago in North America, found large variation in incidence rates in Caucasians, and trends over longer periods have never been studied. OBJECTIVE To estimate the incidence of BD in a Caucasian population in Northern Europe (Maastricht, the Netherlands) between 2003 and 2013. METHODS Primary and histologically confirmed BD, diagnosed in Maastricht, the Netherlands, in the years 2003, 2008, and 2013, was retrieved from a pathology database. Age-standardized and sex-specific incidence rates per 100,000 inhabitants were calculated by using the age distribution of the European standard population of 2013. RESULTS A statistically significant increase in the annual age-standardized incidence rates per 100,000 people was found from 8.1 (95% confidence interval [CI] 3.7–12.5) in 2003 to 68.9 (95% CI 57.2–80.7) in 2013 (p < .001). For women, there was an increase from 7.7/100,000 (95% CI 2.0–13.4) in 2003 to 76.8/100,000 (95% CI 60.2–93.5) in 2013, respectively (p < .001). An increase from 8.8/100,000 (95% CI 1.8–15.9) in 2003 to 59.2/100,000 men (95% CI 42.8–75.6) in 2013 (p < .001) was found. CONCLUSION These findings suggest an increase in the annual age-standardized incidence rates in BD. Address correspondence and reprint requests to: Maud H.E. Jansen, Department of Dermatology, Maastricht UMC+ | azM, P. Debyelaan 25, 6229 HX Maastricht, the Netherlands, or e-mail: maud.jansen@mumc.nl The authors have indicated no significant interest with commercial supporters. © 2019 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.

Mohs Micrographic Surgery at the Skin and Cancer Foundation Australia, 20 Years Later (1997–2017) BACKGROUND The availability of Mohs micrographic surgery (MMS) in Australia has increased dramatically since its inception in the 1980s. OBJECTIVE This study aimed to describe the evolution of MMS practices at the Skin and Cancer Foundation Australia (SCFA) over the past 20 years (1997–2017). METHODS Retrospective analysis of Mohs surgery cases at SCFA in 2017, 2007, and 1997, comparing data on sex, age, tumor type and site, initial tumor and final defect size, number of surgical stages and sections, and closure management. The present study is limited by being a retrospective analysis from a single institution. RESULTS There was a 415% increase in the number of Mohs surgery cases from 1997 to 2017, and a significant increase in Mohs surgery-treated squamous cell carcinoma. The preoperative tumor and final defect size have decreased. More side-to-side closures and fewer grafts are being performed over time. LIMITATIONS Retrospective analysis from a single institution. CONCLUSION Over the last 20 years, MMS has remained appropriate in its application and is being increasingly used for treatment of squamous cell carcinoma suggesting improved access. Address correspondence and reprint requests to: Thomas J. Stewart, BBioMedSc, MBBS, MMed, FRACGP, The Skin & Cancer Foundation Australia, 121 Crown Street Darlinghurst, Sydney, Australia, 2010, or e-mail: thomas_stewart@live.com The authors have indicated no significant interest with commercial supporters. © 2019 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.

Cadaveric Skin Grafts May Greatly Increase the Healing Rate of Recalcitrant Ulcers When Used Both Alone and in Combination With Split-Thickness Skin Grafts BACKGROUND Leg ulcers that do not heal despite appropriate treatment are defined as recalcitrant ulcers. Large surface area, depth, and long duration represent some of most important factors impeding ulcer healing. After sharp debridement, dermal substitutes including skin from cadaver donors may increase the healing rate of recalcitrant ulcers reducing the risk of scar formation and recurrence. OBJECTIVE Assessing if, after sharp debridement, dermal substitutes including skin from cadaver donors may increase the healing rate of recalcitrant ulcers reducing the risk of scar formation and recurrence. PATIENTS AND METHODS Among patients admitted to our hospital for all types of chronic leg ulcers, we retrospectively reviewed the records of patients affected by recalcitrant ulcers (surface greater than 100 cm2, tissue loss involving epidermis, dermis, and subcutaneous tissue, duration longer than 1 year, and showing no healing tendency). After sharp debridement, the ulcers were covered by allografts with strict follow-up after discharge. Multiple allografts were performed when necessary, and a final autograft was applied in case of incomplete healing. RESULTS The records of 414 patients were analyzed. Forty-three patients were lost at follow-up, and the remaining 371 healed after 765 grafting procedures. In 163 patients, the ulcers healed by means of a final autograft. In all the remaining cases, allograft led to ulcer healing. CONCLUSION Allografts represent an effective treatment option in case of recalcitrant, large, deep and long-lasting leg ulcers. Address correspondence and reprint requests to: Giovanni Mosti, MD, Clinica MD Barbantini, Via del Calcio n.2, 55100 Lucca, Italy, or e-mail: giovanni.mosti10@gmail.com The authors have indicated no significant interest with commercial supporters. © 2019 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.

Passive Stereophotogrammetry and Structured Light Scanning for 3-Dimensional Imaging in Dermatologic Surgery No abstract available

A Comparison of Apoptotic Activity for Follicular Unit Extraction Hair Grafts Stored in Different Holding Solutions No abstract available

Introduction No abstract available

Validated Assessment Scales for the Female Asian Calf BACKGROUND Clinical photonumeric scales have been developed and validated to objectively measure the effectiveness of aesthetic treatments in specific anatomical areas; however, these are based on the typical features of Caucasian patients. No clinical scale for Asian calf appearance currently exists. OBJECTIVE To develop and validate a calf assessment scale for use in the female Asian patient population. METHODS AND MATERIALS During 2 validation sessions, 13 raters assessed calf images of female Asian subjects (N = 35) viewed from behind with feet flat on the floor (at rest) and on tiptoes (dynamic). Images were rated from 0 (very slim, linear profile) to 4 (very severe convex profile). RESULTS Inter-rater and intra-rater reliability were "substantial" (≥0.6, intraclass correlation coefficient [ICC] and weighted kappa) for the calf—at rest, calf—dynamic, and calf summary score. Reliability was "substantial" for calf—at rest and calf–dynamic (≥0.6, ICC and weighted kappa) and "almost perfect" (0.85) for the calf summary score. BMI and calf circumference were highly correlated with scale ratings, and calf circumference was a significant predictor. CONCLUSION This new photonumeric assessment scale has value for assessing the female Asian calf, providing a standardized measure of calf appearance in clinical practice and clinical research settings. Address correspondence and reprint requests to: Kyle Seo, MD, PhD, Department of Dermatology, Seoul National University College of Medicine, 101 Daehak-Ro Jongno-Gu, Seoul, Korea, or e-mail: doctorseo@hotmail.com Supported by Merz Pharmaceuticals GmbH, Frankfurt, Germany. The authors received an honorarium for participating in the consensus meeting. The authors have indicated no significant interest with commercial supporters. © 2019 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.

A Challenging Defect of the Nasal Ala No abstract available

Alexandros Sfakianakis
Anapafseos 5 . Agios Nikolaos
Crete.Greece.72100
2841026182

6948891480

alsfakia@gmail.com