How I treat venous thrombosis in children Contraindications to specific antithrombotic therapies in infants and children

Unfractionated heparin

Known allergy

History of HITs

Low-molecular-weight heparin

Known allergy

History of HITs

Invasive procedure within the previous 24 h

Systemic TPA

Known allergy

Active bleeding

Central nervous system ischemia/hemorrhage/surgery within the previous 10 d (includes birth asphyxia)

Surgery within the previous 7 d

Invasive procedure within the previous 3 d

Seizures within the previous 48 h

Thrombolysis by interventional radiology

Known allergy

In cases where needed, inability to place a vena cava filter

Limitations are size of involved vessels and experience of interventionalists

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895344/