Time for change: Renaming Diabetes Insipidus to improve patient safety?

Diabetes Insipidus (DI) is a name given historically to two conditions, which result in ‘diabetes’, which is Greek for ‘syphon’ or polyuria. The “Insipidus” refers to urine being insipid. ‘Cranial DI’ is so called because it relates to a cause within the head characterised by deficiency of vasopressin [antidiuretic hormone (ADH)] secretion from the posterior pituitary. Treatment is with desmopressin, a synthetic long-acting analogue of vasopressin. In contrast ‘Nephrogenic DI’ is due to resistance of the renal tubules to vasopressin action.

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