Viruses, Vol. 10, Pages 42: Vaccinia Virus in Blood Samples of Humans, Domestic and Wild Mammals in Brazil

Viruses, Vol. 10, Pages 42: Vaccinia Virus in Blood Samples of Humans, Domestic and Wild Mammals in Brazil

Viruses doi: 10.3390/v10010042

Authors: Marina Peres Thais Bacchiega Camila Appolinário Acácia Vicente Mateus Mioni Bruna Ribeiro Clóvis Fonseca Vanessa Pelícia Fernando Ferreira Graziele Oliveira Jonatas Abrahão Jane Megid

Outbreaks of Vaccinia virus (VACV) affecting cattle and humans have been reported in Brazil in the last 15 years, but the origin of outbreaks remains unknown. Although VACV DNA have been already detected in mice (Mus musculus), opossums (Didelphis albiventris) and dogs during VACV zoonotic outbreaks, no transmission to cattle or humans from any of these were reported during Brazilian outbreaks. In this work, we assessed the PCR positivity to VACV in blood samples of cows and other domestic mammals, wild rodents and other wild mammals, and humans from areas with or without VACV infection reports. Our results show the detection of VACV DNA in blood samples of cows, horse and opossums, raising important questions about VACV spread.

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