Sleep apnoea in patients with nocturnal hypertension - a multicentre study in the Czech Republic.

Sleep apnoea in patients with nocturnal hypertension - a multicentre study in the Czech Republic.

Physiol Res. 2018 Jan 05;

Authors: Hobzova M, Sonka K, Pretl M, Vaclavik J, Kriegova E, Radvansky M, Zapletalova J, Plackova M, Kolek V

Abstract
Sleep apnoea (SA) is common in patients with hypertension. Nowadays, limited data on the prevalence of SA in nocturnal hypertension (NH) exist. We, therefore, studied the occurrence of SA in Czech patients and its association with 24-hour ambulatory blood pressure monitoring (ABPM), breathing disturbances in sleep, anthropometric data, Mallampati score and Epworth sleepiness scale (ESS) using the Apnea Link device. Undiagnosed SA was found in 72.9% patients (29.3% mild, 26.6% moderate, 17.0% severe) of 188 patients with NH measured by ABPM. The median of the apnoea-hypopnoea index (AHI) was 12.0 (25th-75th percentile 5.0-23.8). Moderate/severe SA (AHI>/=15) was associated with BMI, waist circumference, mean night saturation SpO(2), t90, oxygen desaturation index (ODI), ESS (daytime BP only) (p</=0.032), but not ABPM parameters and Mallampati score (p>0.09). A likelihood of moderate/severe SA was enhanced by ODI>14.5 events/h (odds ratio=57.49, 95%CI=22.79-145.01), t90>6.5% (8.07, 4.09-15.92), mean night SpO(2)<93.5% (3.55, 1.92-6.59), BMI>29.05kg/m(2) (6.22, 3.10-12.49), circum waist>105.5 cm (3.73, 1.57-8.83), but not by any ABPM parameter. In conclusion, a high incidence of SA (72.9%) was observed in Czech patients with NH. SA severity was associated with body characteristics and oxygenation parameters, but not with ABMP parameters and Mallampati score.

PMID: 29303603 [PubMed - as supplied by publisher]

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