Abstract
Adult T-cell lymphoma/leukemia (ATLL) is a hematologic malignancy of mature CD4-positive T-cells associated with chronic infection by human T-lymphotropic virus 1 (HTLV-1). Four different subtypes of ATLL have been described: acute, lymphomatous, chronic and smoldering forms. ATLL prognosis remains poor, with overall survival duration depending on the subtype, because there is no curative treatment of ATLL and patients often suffer from opportunistic infections.
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