Optimization of affinity and microsomal stability led to identification of the potent, metabolically stable fenobam analog 4l. Robust in vivo efficacy of 4l was demonstrated in four different models of anxiety. Additionally, a ligand based pharmacophore alignment of fenobam and MPEP is proposed.
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Women in Love by . Lawrence. Searchable etext. Discuss with other readers. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Ino...
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<span class="paragraphSection"><div class="boxTitle">Abstract</div><div class="boxTitle"...
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