The complexity and cellular diversity of the adult brain arises from the proliferation and differentiation of a small number of stem cells. The intrinsic state of stem cells depends on their spatial and temporal history and affects their responsiveness to extrinsic signals from the microenvironment. Stem cell self-renewal and differentiation along neuronal and glial lineages are defined by the dynamic interplay between transcription, epigenetic control, and posttranscriptional regulators, including microRNAs, whose key role in stem cell biology is just emerging.
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IZE is a professional association dedicated to expanding the educational impact of zoos and aquariums worldwide, to enhance the understandin...
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Copyright © 1999-2007 by , Kai Froeb. Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free ...
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