The peroxisome-proliferator-activated-receptor-γ (PPARγ) is a member of the nuclear receptor superfamily that plays a critical role in diverse biological processes, including adipogenesis, lipid metabolism, and placental development. To study the activity of PPARγ, we constructed two new reporter genes: a fluorescent GFP-tagged histone-2B (PPRE-H2B-eGFP) and a secreted nanoluciferase (PPRE-pNL1.3[secNluc]). This study demonstrates their usage to monitor PPARγ activity in different cell types and screen for PPARγ’s potential ligands.
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2z9dG5d
via IFTTT
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δημοφιλείς αναρτήσεις
-
Background. Reconstruction of surgical defects following cranial base surgery is challenging. Others have demonstrated that leukocyte-platel...
-
During lytic infection, herpes simplex virus (HSV) DNA is replicated by a mechanism involving DNA recombination. For instance, replication o...
-
IJMS, Vol. 18, Pages 1603: Induction of a Regulatory Phenotype in CD3+ CD4+ HLA-DR+ T Cells after Allogeneic Mixed Lymphocyte Culture; Indic...
-
Dracaena cochinchinensis Lour. is an ethnomedicinally important plant used in traditional Chinese medicine known as dragon’s blood. Excessiv...
-
Taking a slurry reservoir-pipeline-valve system as research object, axial dynamic vibrations of pipe system were induced by coupled hydrauli...
-
Women in Love by . Lawrence. Searchable etext. Discuss with other readers. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Ino...
-
by Emily M. Zygiel, Karen A. Noren, Marta A. Adamkiewicz, Richard J. Aprile, Heather K. Bowditch, Christine L. Carroll, Maria Abigail S. Cer...
-
Publication date: February 2017 Source: Cryobiology, Volume 74 Author(s): Reza Masoudi, Ahmad Zare Shahneh, Armin Towhidi, Hamid Kohram, A...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου