Radiation-induced lung injury is common after stereotactic body radiotherapy (SBRT). For the first time, we characterized post-SBRT lung injury using computed tomography (CT)-based radiomics for 14 patients. Radiomic features significantly correlated with radiation oncologist-scored lung injury and showed significant dose-response relationships, suggesting the potential for radiomics to provide a quantitative, objective measurement of post-SBRT lung injury.
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