Τρίτη 23 Μαΐου 2017

PET-MRI of the Pancreas and Kidneys

Abstract

Purpose of Review

PET-MRI is a novel imaging modality which can non-invasively provide both morphological and functional information about benign and malignant lesions. In this article, recent updates in the applications of PET-MRI in pancreatic and renal cancers are reviewed.

Recent Findings

Multiparametric imaging has raised great interest in the oncology field by revealing various functional characteristics within tumors. For example, we can quantify tumor perfusion by dynamic contrast-enhanced MRI or arterial spin labeling MRI, tumor cellularity by diffusion-weighted image, tumor metabolites by MR spectroscopy, tumor metabolism by FDG-PET, and tumor heterogeneity by radiomics. Recent studies have demonstrated that these imaging biomarkers were correlated with tumor aggressiveness, treatment response, and prognosis.

Summary

Combination of these imaging biomarkers from "one-stop shop" PET-MRI has great potential to more accurately characterize and monitor tumor behavior in the clinic to deliver individualized treatment plans.



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