Myocyte enhancer factor 2D (MEF2D) is involved in many aspects of cancer progression, including cell proliferation, invasion, and migration. However, little is known about the role of MEF2D in tumor angiogenesis. Using clinical specimens, colorectal cancer (CRC) cell lines and a mouse model in the present study, we found that MEF2D expression was positively correlated with CD31-positive microvascular density in CRC tissues. MEF2D promoted tumor angiogenesis in vitro and in vivo and induced the expression of proangiogenic cytokines in CRC cells.
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Cancer is associated with genomic instability and aging. Genomic instability stimulates tumorigenesis, whereas deregulation of oncogenes acc...
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Eribulin is one of the newer chemotherapeutic agents approved for use in later line treatment of patients with metastatic breast cancer. Pha...
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<span class="paragraphSection"><div class="boxTitle">Abstract</div>It is not clear whether breast canc...
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Abstract Helmet manufacturers recommend replacing a bicycle helmet after an impact or after anywhere from 2 to 10 years of use. The goal o...
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Summary Emergency cricothyrotomy is a common feature in all difficult airway algorithms. It is the final step following a ‘can't intub...
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Publication date: 10 June 2017 Source: Journal of Controlled Release, Volume 255 Author(s): Ožbej Zupančič, Andreas Bernkop-Schnürch Pept...
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Ocular Vestibular Evoked Myogenic Potentials: Where Are We Now? Objective: Over the last decade, ocular vestibular evoked myogenic potential...
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ACS Nano DOI: 10.1021/acsnano.7b01172 from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2qaCNQg via...
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Scleraxis (Scx) is a known regulator of tendon development, and recent work has identified the role of Scx in bone modeling. However, the ro...
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