Myocyte enhancer factor 2D (MEF2D) is involved in many aspects of cancer progression, including cell proliferation, invasion, and migration. However, little is known about the role of MEF2D in tumor angiogenesis. Using clinical specimens, colorectal cancer (CRC) cell lines and a mouse model in the present study, we found that MEF2D expression was positively correlated with CD31-positive microvascular density in CRC tissues. MEF2D promoted tumor angiogenesis in vitro and in vivo and induced the expression of proangiogenic cytokines in CRC cells.
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2paqxw9
via IFTTT
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δημοφιλείς αναρτήσεις
-
Abstract Cardiomyopathy, also known as heart muscle disease, is an unfavorable condition leading to alterations in myocardial contraction ...
-
Background Hyperthyroidism is associated with increased thrombotic risk. As contact system activation through formation of neutrophil extrac...
-
Liver ischemia reperfusion injury (IRI) is inevitable during transplantation and resection and is characterized by hepatocellular injury. Th...
-
Abstract With the aid of the Mach–Zehnder interferometer, the drawability of polypropylene fibres (PP) was optically studied. The effect o...
-
Abstract Understanding the spatial distribution of PM 2.5 concentration and its contributing environmental variables is critical to devel...
-
Accuracy of the Compressed Sensing Accelerated 3D-FLAIR Sequence for the Detection of MS Plaques at 3T. AJNR Am J Neuroradiol. 2...
-
Radioterapia oncologica, la Cattolica protagonista al Congresso Europeo insalutenews ... l'utilizzo della radioterapia stereotass...
-
Abstract Background Individualized medication reviews may improve our understanding of the distribution of CYP2C19 polymorphisms in ethn...
-
Abstract Biodegradable polymer blends of high-molecular-weight poly(3-hydroxybutyrate) (PHB) and poly(lactic acid) (PLA) are not miscible ...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου