The chromatin remodeler AT-Rich Interactive Domain 1A (ARID1A) is frequently mutated in ovarian clear cell carcinoma (OCCC) and endometriosis precursor lesions. Here, we show that knocking down ARID1A in an immortalized endometriosis cell line is sufficient to induce phenotypic changes indicative of neoplastic transformation as evidenced by higher efficiency of anchorage-independent growth, increased propensity to adhere to collagen, and greater capacity to invade basement membrane extract in vitro.
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Background. Reconstruction of surgical defects following cranial base surgery is challenging. Others have demonstrated that leukocyte-platel...
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During lytic infection, herpes simplex virus (HSV) DNA is replicated by a mechanism involving DNA recombination. For instance, replication o...
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Outcomes of multimodal management for sinonasal squamous cell carcinoma. J Craniomaxillofac Surg. 2017 May 12;: Authors: Paré A, Blan...
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Abstract Purpose Low back pain is a significant problem for school-aged athletes. Although some risk factors relating to sports activiti...
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Thyroid cancer is the most common malignant tumor of the endocrine system and the incidence has been increasing in recent years. In a great ...
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