Local Intraluminal Irrigation With Argatroban During Free Flap Repair in a Patient With Heparin-Induced Thrombocytopenia.

Local Intraluminal Irrigation With Argatroban During Free Flap Repair in a Patient With Heparin-Induced Thrombocytopenia.

Ann Otol Rhinol Laryngol. 2017 May;126(5):407-410

Authors: Macias D, Kwon DI, Walker PC, Peterson NR

Abstract
OBJECTIVE: This study describes a case of a successful free flap repair using argatroban for local intraluminal irrigation as a substitute to heparin in a patient with heparin-induced thrombocytopenia.
METHODS: Case report and review of literature.
RESULTS: The patient had an uneventful postoperative course, and the free flap survived without complications.
CONCLUSIONS: The use of argatroban during microvascular surgery is likely to be safe and simple and may be effective in preventing micro-thrombotic complications during microvascular surgery, and it should be considered as an alternative to heparinized saline for local intraluminal irrigation.

PMID: 28397565 [PubMed - in process]

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