A 32-year-old man with a history of intravenous drug use was admitted to the hospital for evaluation of intermittent fever and chills over the course of several weeks. On examination, the temperature was 39.0°C and pulse rate 110 bpm. A grade 2/6 holosystolic murmur was appreciated at the left lower sternal border. Transthoracic echocardiography with agitated saline contrast demonstrated an echodensity on the septal leaflet of the tricuspid valve associated with mild tricuspid regurgitation and a right-to-left shunt. Blood cultures grew methicillin-resistant Staphylococcus aureus. On the third day of hospitalisation, mild conjunctival erythema of the right eye was observed, which was associated with discomfort and a subjective decrease in vision. Visual fields on confrontation revealed a large inferior scotoma. Bedside indirect ophthalmoscopy established the presence of a yellow, elevated subretinal mass ~10 times the diameter of the optic disc, adjacent to the superior-temporal vascular arcade, with associated intraretinal...
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