Heparanase activity is highly implicated in cellular invasion and tumor metastasis, a consequence of cleavage of heparan sulfate and remodeling of the extracellular matrix underlying epithelial and endothelial cells. Heparanase expression is rare in normal epithelia, but is often induced in tumors, associated with increased tumor metastasis and poor prognosis. In addition, heparanase induction promotes tumor growth, but the molecular mechanism that underlines tumor expansion by heparanase is still incompletely understood.
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Publication date: June 2017 Source: Anesthesiology Clinics, Volume 35, Issue 2 Author(s): Anair Beverly, Alan D. Kaye, Olle Ljungqvist, R...
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At the King’s Fund’s annual conference on leadership and management last week, NHS England’s chief executive, Simon Stevens, found an innova...
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Abstract Kimchi was prepared with different types of salts: purified salt (PS), solar salt aged for 1 year (SS1), aged for 3 years (SS3), a...
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Abstract Although Nobori ® , with a bioresorbable polymer and biolimus A9 abluminal coating, has unique characteristics, few data exist re...
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Abstract In this study we investigated whether exerting an impulse on a Chronic Total Occlusion (CTO) improves the success rate of CTO cro...
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Zusammenfassung Nichtmelanozytärer Hautkrebs und seine Frühformen sind aufgrund von steigender Inzidenz und Prävalenz häufige Diagnosen im...
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Abstract Background The role of thymectomy in the treatment of juvenile myasthenia gravis (JMG) is poorly defined. The objective of this...
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