Radiotherapy is an important treatment modality in the management of locally advanced non-small cell lung cancer (NSCLC). However, radioresistance markedly impairs its efficacy in clinic. Bromodomain and extra-terminal (BET) bromodomain inhibitors have demonstrated dramatic antitumor activity in several preclinical human cancer models. In this study, we investigated for the first time the effect of JQ1, a novel BET Bromodomain inhibitor, on tumor cell radiosensitivity of NSCLC in vitro and in vivo.
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2kFTDEV
via IFTTT
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δημοφιλείς αναρτήσεις
-
Many different quantitative techniques have been developed to either assess Environmental Justice (EJ) issues or estimate exposure and dose ...
-
Leddsmerter kan ha mange årsaker. Traumatiske, immunologiske og infeksiøse lidelser må vurderes. En god anamnese kan sette oss på rett spor...
-
Outcomes of Drug-Induced Sleep Endoscopy-Directed Surgery for Pediatric Obstructive Sleep Apnea. Otolaryngol Head Neck Surg. 2017 Nov ...
-
Evidence-Based Medicine: Cleft Palate. Plast Reconstr Surg. 2017 Jan;139(1):191e-203e Authors: Woo AS Abstract LEARNING OBJECTIVES:...
-
Trends in Otolaryngology Consultation Patterns at an Academic Quaternary Care Center. JAMA Otolaryngol Head Neck Surg. 2017 Jan 05;: ...
-
Apple, Facebook, Google and Microsoft claim the president’s ban on people from seven Muslim-majority countries inflicts "substantial ha...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου