Τρίτη 31 Ιανουαρίου 2017

{beta}-Catenin haploinsufficiency promotes mammary tumorigenesis in an ErbB2-positive basal breast cancer model [Cell Biology]

Aberrant activation of β-catenin through its activity as a transcription factor has been observed in a large proportion of human malignancies. Despite the improved understanding of the β-catenin signaling pathway over the past three decades, attempts to develop therapies targeting β-catenin remain challenging, and none of these targeted therapies have...

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