An “up, no change, or down” system: time-dependent expression of mRNAs in contused skeletal muscle of rats used for wound age estimation

The determination of wound age is important in medicolegal traumatology, but remains a challenging application in forensic medicine. In forensic pathology, it is often important to estimate wound age as accurately as possible, especially when there are several injuries that were caused by multiple abusers or vehicles within narrow intervals, in view of the value of wound age in the reconstruction of crime scenes and the determination of the cause of death [1]. However, as yet, no parameter has been shown to be sufficiently accurate to distinguish the minimal interval of an early wound in court.

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