MRI-guided functional anatomy approach to prostate brachytherapy

Publication date: Available online 29 December 2016
Source:Brachytherapy
Author(s): Payal D. Soni, Alejandro Berlin, Aradhana M. Venkatesan, Patrick W. McLaughlin
PurposeTo provide an MRI based functional anatomy guide to prostate brachytherapy.Methods and MaterialsWe performed a narrative review of periprostatic functional anatomy and the significance of this anatomy in prostate brachytherapy treatment planning.ResultsMRI has improved delineation of gross tumor and critical periprostatic structures that have been implicated in toxicity. Furthermore, MRI has revealed the significant anatomic variants and the dynamic nature of these structures that can have significant implications for treatment planning and dosimetry.ConclusionsThe MRI-based functional anatomy approach to prostate brachytherapy takes into account extent of disease, its relation to the patient's individual anatomy, and functional baseline to optimize the therapeutic ratio of prostate cancer treatment.



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