2016-10-24T02-06-58Z
Source: Oxidants and Antioxidants in Medical Science
V. V. Sathibabu Uddandrao, Parim Brahmanaidu, Balaji Meriga, Ganapathy Saravanan.
Successful regulation of cellular equilibrium among oxidation and anti-oxidation is significant for cellular function and DNA integrity as well as gene expression for signal transduction. Numerous pathological processes, such as cancer, diabetes, heart and/or kidney diseases, Parkinsons and Alzheimers diseases, have been revealed to be associated to the redox state of cells. In a challenge to curtail the onset of oxidative stress, administration with diverse recognized antioxidants has been recommended. Glutathione (GSH) is accepted for its capability to reduce oxidative stress and downstream the harmful effects such as lipid peroxidation. Antioxidants thus play a significant part in protecting the human body against the damage caused by reactive oxygen species. S-Allylcysteine (SAC), a sulfur containing amino acid derived from garlic, has been experimentally demonstrated to possess antioxidant and other beneficial activities. In the present review, we addressed the therapeutic effects of SAC as a potential antioxidant on various disorders by increasing GSH and other antioxidants. Authenticated with a number of in vivo, in vitro, animal experiments and some human clinical trials, beneficial effects of SAC were reported in cancer, neurodegeneration, nephrotoxicity, ischemic stroke, myocardial infarction and other heart diseases, Alzheimers disease, Parkinsons disease, preeclampsia and diabetes mellitus. On the other hand, there is no scientific evidence against SAC for having adverse effects.
http://ift.tt/2eJjHrs
Δευτέρα 24 Οκτωβρίου 2016
The potential role of S-allylcysteine as antioxidant against various disorders in animal models
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δημοφιλείς αναρτήσεις
-
Objective Outpatient parenteral antimicrobial therapy (OPAT) provides opportunities for improved cost savings, but in the UK, implementation...
-
Abstract Purpose Overcoming the flaws of current data management conditions in head and neck oncology could enable integrated informatio...
-
http://orl-agios.blogspot.com/2017/06/the-preclinical-anticancer-effect-of.html Flavonoids present in foods were considered non-absorbable b...
-
Vol.31 No.5 from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1k8FKtW via IFTTT
-
Universal newborn hearing screening (UNHS) has become the standard of care in many countries. The aim of this study was to evaluate the resu...
-
Geographic region: Does it matter in cutaneous melanoma of the head and neck? Laryngoscope. 2017 Jun 05;: Authors: Kılıç S, Unsal AA,...
-
The overall objective of the guideline is to provide up-to-date, evidence-based recommendations for the management of lichen sclerosus (LS)...
-
Abstract The head-mounted display (HMD) has the potential to improve the quality of ultrasound-guided procedures. The aim of this non-clin...
-
http://ift.tt/2pnwWaQ
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου