Anemia in patients with type II diabetes mellitus with and without diabetic retinopathy

2016-09-26T11-08-59Z
Source: International Journal of Medical Science and Public Health
Shikha Baisakhiya, Punita Garg, Surjit Singh.
Background: Anemia has been recognized as a chronic complication of diabetes mellitus. Oxidative stress created by chronic hyperglycemia leads to RBC damage and is involved in the pathogenesis of anemia. Anemia induced hypoxia leads to vaso-proliferation in the retina and in turn to development and deterioration of diabetic retinopathy. Objective: The aim of the study was to find out whether anemia is prevalent in cases of type II diabetes mellitus (DM). To find out whether there exist a relationship between anemia and diabetic retinopathy. Materials and Methods: The study was done on total 135 subjects. The control group (Group-A) included 45 age and sex matched healthy subjects. The case group was divided into 2 groups, 45 subjects diagnosed with type II DM without diabetic retinopathy (Group-B) and 45 subjects of type II DM with diabetic retinopathy (Group-C). The mean hemoglobin level, total red blood cell (RBC) count and packed cell volume (PCV) were compared in 2 groups. Result: The mean hemoglobin level in Group-A, B, and C were 14.23±0.83 gm/dl, 12.22±0.11 gm/dl, and 10.44±0.23 gm/dl, respectively (p


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