Food allergy is associated with colonization in children with atopic dermatitis

Atopic dermatitis (AD) commonly precedes the development of food allergy.1 The reasons for this close association are not well characterized. Recent studies in patients with AD found that peanut allergy was associated with filaggrin (FLG) mutations.1,2 This finding suggests that skin barrier dysfunction contributes to the development of food allergy by promoting epicutaneous allergen absorption and sensitization. However, FLG mutations are absent in most patients with AD,1 and a recent study conducted in the United States did not demonstrate the close relationship between peanut allergy and FLG mutations in children with AD.

from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Yiaw2t
via IFTTT