Πέμπτη 14 Απριλίου 2022

Augmentation of the width and thickness of keratinised gingiva using a collagen biomaterial in apically positioned flap surgery: A technical note

alwin shared this article with you from Inoreader
To ensure that dental implants remain functional in the long-term, adequate thickness and width of keratinised tissue at the cervical collars are essential.1 Once a tooth is lost, the height of the alveolar bone is reduced, and the keratinised tissue of the edentulous area recedes.2 There are two techniques currently used to obtain the desired keratinised tissue augmentation: the apically positioned flap surgery and the free gingival graft surgery.2 The apically positioned flap surgery, the existing keratinised tissue is incised at the mucosal or mucoperiosteal flap to enable natural extension of the incised end. (Source: The British Journal of Oral and Maxillofacial Surgery)
View on the web

SEARCH FOR EXPERIMENTAL EVIDENCE OF DOSE-RATE AND WALL SCATTERING EFFECTS IN THE THERMOLUMINESCENCE RESPONSE OF LIF:MG,TI (TLD-100)

alwin shared this article with you from Inoreader
Abstract
An experimental investigation into the possibility of dose-rate effects and wall scatter in the thermoluminescent response of LiF:Mg,Ti (TLD-100) was carried out. The investigation was motivated by theoretical simulations predicting the possible presence of dose-rate effects coupled with the lack of detailed experimental studies. The dose rate was varied by changing the source to sample distance, by the use of attenuators, sources of 137Cs of various activities, filtration and the construction of identical geometrical irradiators of Teflon and stainless steel. Four levels of dose in the linear dose response region were studied at 10−2 Gy, 1.5 × 10−2 Gy, 0.1 Gy and 0.5 Gy to avoid complications in interpretation due to supralinearity above 1 Gy. At the dose of 1.5 × 10−2 Gy, the dose rate was varied by five orders of magnitude from 4.9 × 10−3 Gy s−1 to 4.9 × 10− 8 Gy s−1. At the other levels of dose, a one to two orders of magnitude in dose rate was achieved. Within the measurement uncertainty of 5–10%, no dose-rate effects were observed in any of the experimental measurements and no changes in the shape of the glow curve were observed. The maximum wall scatter effect (Teflon to stainless steel) was measured at ~8% within the experimental uncertainty and well below expectations. The results are encouraging with respect to the accurate and reproducible use of LiF:Mg,Ti under various experimental conditions of irradiation.
View on the web

DESIGN AND FABRICATION OF A PEDIATRIC THYROID PHANTOM FOR USE IN RADIO-IODINE UPTAKE MEASUREMENT, IMAGE QUALITY CONTROL AND DOSIMETRY

alwin shared this article with you from Inoreader
Abstract
Estimating internal contamination from 131I for children in nuclear accidents is a crucial subject in the radiation protection field. Throughout this paper, an urgent and simple method was proposed for measuring 131I inside the pediatric thyroid gland by constructing a neck and thyroid phantom. For this purpose, CT scan images of healthy child's thyroids were obtained, and the sizes of different parts were determined by a 3D slicer image processing software. Girls with the body surface area between 0.95 and 1.05 were involved in this study. The fabricated phantom is composed of 5 cylindrical slabs of 2-cm thickness, and several small holes were constructed for TLD dosemeters near the thyroid gland and all other parts of the neck. The phantom was constructed utilizing a 3D printer with acrylonitrile butadiene styrene plastic. The thyroid phantom was filled with radioiodine-131, and calibration curves were plotted for contam ination estimation. A nodular thyroid phantom was also constructed. The nodular phantom or the resolution phantom has 4 removable parts containing cylindrical holes with diameters of 3, 6, 9 and 12 mm. These holes on the thyroid glands can be filled with different activities of radionuclides to serve as hot and cold spots for quality control of nuclear medicine images. The results show that the designed phantom is applicable in different fields such as nuclear image quality and resolution tests, dosimetry and iodine thyroid uptake estimation in nuclear medicine departments, and nuclear emergency monitoring.
View on the web

Τρίτη 12 Απριλίου 2022

Post-Progression Treatments after Palbociclib plus Endocrine Therapy in HR+/HER2- Metastatic Breast Cancer Patients: What Is the Better Choice?

alwin shared this article with you from Inoreader
Via Oncology
CONCLUSIONS: patients who were progressive on P+ET could still benefit from a subsequent ET. In patients who experienced a good efficacy from prior ET, without visceral metastatic sites, HT seems the most suitable option, when compared to CT, also in terms of safety.PMID:34875670 | DOI:10.1159/000521252 (Source: Oncology)
View on the web

Status of IDH mutations in chondrosarcoma of the jaws

alwin shared this article with you from Inoreader
The aim was to analyse the relationship between mutations of the isocitrate dehydrogenase gene (IDH) and clinical characteristics of chondrosarcoma of the jaw in order to provide new information on its molecular pathology. Tissue samples were collected from 25 patients diagnosed with chondrosarcoma of the jaw. IDH mutations were detected through polymerase chain reaction and direct sequencing. Clinicopathological data were analysed retrospectively. The study included 14 female and 11 male patients; the median patient age was 38 years. (Source: International Journal of Oral and Maxillofacial Surgery)
View on the web

Poor Treatment Outcomes with Second-Line Chemotherapy in Advanced Synovial Sarcoma

alwin shared this article with you from Inoreader
Via Oncology
CONCLUSION: Our exploratory study revealed that the response rate of second-line chemotherapy regimens for patients with synovial sarcoma was 9.4%. Therefore, there is an urgent need to develop more active therapeutic regimens for synovial sarcomas.PMID:35405680 | DOI:10.1159/000524500 (Source: Oncology)
View on the web

NeuroEMCrit – Time is Brain – Acute Ischemic Stroke Part 2: Mechanical Thrombectomy

als.fakia shared this article with you from Inoreader

Thrombectomy-2-scaled.jpg

part II of the stroke update...

EMCrit Project by NeuroEMCrit Team (Casey & Neha).

View on the web

Δημοφιλείς αναρτήσεις